Peptide permeases from Streptococcus pneumoniae affect adherence to eucaryotic cells
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چکیده
منابع مشابه
Factor H Binding to PspC of Streptococcus pneumoniae Increases Adherence to Human 1 Cells
Factor H Binding to PspC of Streptococcus pneumoniae Increases Adherence to Human 1 Cells Lines In Vitro and Enhances Invasion of Mouse Lungs In Vivo. 2 Running title: Complement FH enhances pneumococcal adherence. 3 4 Lisa R. Quin 1 , Chinwendu Onwubiko 1 , Quincy C. Moore 1 , Megumi Fujioka Mills 1 , Larry S. 5 McDaniel 123* , and Stephanie Carmicle 1† 6 Departments of Microbiology 1 , Surger...
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To study carbohydrate-mediated adherence of Streptococcus pneumoniae to the human airway, we measured binding of live S. pneumoniae organisms to a cultured cell line derived from the lining of the conjunctiva and to primary monolayers of human bronchial epithelial cells in the presence and absence of oligosaccharide inhibitors. Both encapsulated and nonencapsulated strains of S. pneumoniae grow...
متن کاملAdherence of Streptococcus pneumoniae to human bronchial epithelial cells (BEAS-2B).
Pneumococcal adherence to alveolar epithelial cells and nasopharyngeal epithelial cells has been well characterized. However, the interaction of Streptococcus pneumoniae with bronchial epithelial cells has not been studied. We have now shown that pneumococci bind specifically to a human bronchial epithelial cell line (BEAS-2B cells). Pneumococci adhered to BEAS-2B cells in a time- and dose-depe...
متن کاملPavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation.
Pneumococcal adherence and virulence factor A (PavA) is displayed to the cell outer surface of Streptococcus pneumoniae and mediates pneumococcal binding to immobilized fibronectin. PavA, which lacks a typical gram-positive signal sequence and cell surface anchorage motif, is essential for pneumococcal virulence in a mouse infection model of septicemia. In this report the impact of PavA on pneu...
متن کاملPolyinosine-polycytidylic acid enhances cellular adherence of Streptococcus pneumoniae.
OBJECTIVES/HYPOTHESIS Viral upper respiratory tract infections (URIs) are often followed by secondary bacterial infections. To better understand this phenomenon, we examined the impact of the viral agent polyinosine-polycytidylic acid [Poly (I:C)] on the adherence of Streptococcus pneumoniae (Spn) to pharyngeal epithelial cells. STUDY DESIGN In vitro model of cultured human pharyngeal epithel...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1995
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.63.7.2493-2498.1995